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The Vu Lab

Members

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Tania Vu, Ph.D.
Principal Investigator

Dr. Vu develops enabling cytometry imaging technologies that advance understanding of cellular signaling, cellular heterogeneity, and combination drug testing. A current major focus of translational work is the application of miniaturized imaging platforms to assess drug response in small samples of primary patient single cell subpopulations in leukemia, breast cancer, and neurons. Dr. Vu has a demonstrated history of high-impact journal publications and invited conference presentations. She is an associate professor in the Department of Biomedical Engineering, and a member of the Knight Cancer Institute and Oregon Center for Spatial Systems Biomedicine at Oregon Health and Science University in Portland, Oregon.

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Thomas Jacob, Ph.D.
Senior Research Associate

Dr. Jacob earned MS degree in Biophysics from MG University, India and his PhD in Molecular Biology the joint program at MK University India and Max Planck Institute for Cell Biology, Germany. Dr. Jacob conducted postdoctoral work at the OHSU Center for Biomarker Discovery, in the field of proteomics of neural stem cell development and was a Research Associate where he developed various proteomic assay (immuno-, mass spec) technologies for identifying protein biomarkers of various pregnancy associated disorders. He participated in forming an OHSU spinout Proteogenix Inc, where he was staff scientist. In 2010, Dr. Jacob returned to OHSU as senior associate in the Vu Lab at the School of Medicine, OHSU. His focus is developing single cell imaging assay technologies for analyzing cancer drug effectiveness and cellular responses, primarily in hematological malignancies. Dr. Jacob has served as principal investigator in multiple SBIR/Industry sponsored research projects, has authored 20+ peer reviewed publications, and an inventor on two issued patents.

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Bridget Robinson, Ph.D.
Pre-clinical Translation Scientist

Dr. Robinson earned her PhD in Molecular Microbiology and Immunology from OHSU in 2011 in Dr. Scott Wong’s lab, within the Vaccine and Gene Therapy Institute. Her work utilized a non-human primate model of Kaposi’s Sarcoma-associated Herpesvirus to study immune evasion mediated by a family of viral proteins (viral interferon regulatory factors). During her post-doctoral fellowship with Dr. Jaisri Lingappa at the University of Washington in Seattle, she focused on molecular interactions between Gag molecules and viral RNA during HIV assembly. She returned to OHSU for continued post-doctoral work with Dr. Tim Nice, studying host mediated control of a viral protein during persistent norovirus infection. Dr. Robinson’s research interests are the molecular biology of virus- host interactions, infectious disease, and cancer.

Former Lab Members

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